Returning to physical activity after covid-19

SUMMARY: Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state accompanied by unique brain imaging pattern typically associated with number of complex clinical conditions including: preeclampsia/eclampsia, allogeneic bone marrow transplantation, solid organ autoimmune diseases and high dose cancer chemotherapy. The mechanism behind the developing vasogenic edema CT or MR appearance PRES not known. Two theories have historically been proposed: 1) Severe hypertension leads to failed auto-regulation, subsequent hyperperfusion, endothelial injury/vasogenic and; 2) vasoconstriction hypoperfusion ischemia edema. strengths/weaknesses these hypotheses are reviewed in translational fashion including supporting evidence current available imaging/clinical data related that develop PRES. While hypertension/hyperperfusion theory has most popular, similar immune challenge present T-cell/endothelial cell activation may be basis leukocyte trafficking systemic/cerebral vasoconstriction. These systemic features along vascular perfusion appear render strong support for older coupled as mechanism.